A white caffeine pouch held between two fingers

How long does caffeine last? Half-life explained

Updated

Caffeine has an average half-life of about four hours in healthy adults, with a range of two to eight hours, according to the European Food Safety Authority (EFSA). That means about half the caffeine from a drink is still in your body four hours later. How long it lasts varies from person to person, depending on things like age, body weight, pregnancy, medication and liver health.

Key points
• Average half-life of caffeine: about 4 hours (range 2–8 hours) in healthy adults.
• After about 8 hours, roughly a quarter of the caffeine is still in the body (at a 4-hour half-life).
• Pregnancy, some medicines and liver health can make caffeine last longer.
• EFSA says 100 mg of caffeine close to bedtime may affect sleep in some adults.

Table of contents

What is caffeine's half-life?

The half-life is the time it takes the body to get rid of half of the caffeine. EFSA explains that in healthy adults the average half-life is about four hours, ranging from two to eight hours (EFSA explains: caffeine).

How much caffeine is left after a few hours?

An example with a cup of instant coffee (about 100 mg, according to the NHS), at the average half-life of four hours:

Time after drinking Caffeine still in the body (approx.)
0 hours 100 mg
4 hours 50 mg
8 hours 25 mg
12 hours 12.5 mg

Work out your own total: caffeine calculator.

Illustration only, based on a 4-hour half-life. With a half-life of 8 hours, half would still be there after 8 hours.

If you have caffeine several times a day, the amounts overlap. More on daily totals: How much caffeine is too much?

Why it varies from person to person

According to EFSA, the half-life varies widely depending on:

Sensitivity to caffeine also varies, so the same amount can feel different for different people. More: Caffeine sensitivity

Caffeine later in the day

EFSA notes that a single dose of 100 mg (about 1.4 mg per kg of body weight) may affect sleep duration and patterns in some adults, particularly when consumed close to bedtime. With a half-life of several hours, caffeine from the afternoon can still be in your body in the evening.

To keep track, check the caffeine per serving:

Source Caffeine
Instant coffee, 1 cup about 100 mg
Espresso, 60 ml about 80 mg
Tea, 1 cup about 75 mg
Energy drink, 250 ml about 80 mg
Cola, 1 can about 40 mg
Decaf coffee, 200 ml about 4 mg
Optimal Native Morning Energy / Daily Flow / Evening Relax, 1 pouch 200 mg / 75 mg / 0 mg

Drinks: NHS; espresso and decaf: EUFIC. More: Caffeine in an espresso · Caffeine in decaf coffee

FAQ

How long does caffeine stay in your system?
The average half-life is about four hours in healthy adults (range 2–8 hours), so it takes several half-lives for most of it to be cleared.

How long does a cup of coffee last?
At a 4-hour half-life, about half of the caffeine is still in the body four hours later and about a quarter after eight hours.

Why does caffeine last longer for some people?
Age, body weight, pregnancy, medication and liver health all affect how fast caffeine is cleared.

What happens if you stop caffeine suddenly?
Regular users can get withdrawal symptoms such as headache. More: Caffeine withdrawal

Read next: Caffeine withdrawal · How much caffeine is too much? · Caffeine in coffee vs tea vs green tea

Optimal Native is coming to the UK. One stack for the whole day: Morning Energy, Daily Flow and Evening Relax. Pre-orders ship from 15 December 2026.

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